If a conversation icon appears faded, and you cannot speak to the other character about this subject when you click on the icon, first search for this particular inventory item, then return to engage in conversation about this item.

Do not ignore any hot spots in the gameplay. An item you pick up in one area may come in very useful further on in the game. Think also how you can combine inventory items for a different use - a matchbox and a sugar cube might just attract a tasty treat...

Carfax

Do not attempt to defeat the monsters with the gun. Use the sunlight peering through the windows to your advantage by blocking the door to the adjacent room to buy you some time. Even maybe take a leap of faith after…

In the garden, you will find a cement box. You will need to have the wire cutters and something to lubricate the hinges. Once the grate is open, the space looks just perfect for a drawing...and interesting how the illustrations resemble the carved knobs....

Asylum - 2nd Visit

Be sure to find Mina's wedding ring within Seward's Office as it will be needed to continue conversation with Hopkins inside the Jail Cell.
When making the Vampire Serum, though the book reads to have the burner at 30 degrees Celsius, listen to the correction on the tape recorder to what the proper temperature should be.

Highgate Cemetery - 2nd Visit

The stone gargoyles may be watching your every move. Using the assembled vampire radio transmitter, aim at anything you can think of: the walls, the crypts, the entranceway columns. There are 3 gargoyle heads to be found and destroyed.

Castle Library

The Geometric Parchment Puzzle - Using a real clock as a reference, press the following 4 buttons to solve the puzzle: 3 o'clock, 12 o'clock, 6 o'clock, 4 -5 o'clock.